Structure of bacterial oligosaccharyltransferase PglB bound to a reactive LLO and an inhibitory peptide

Oligosaccharyltransferase (OST) is a key enzyme of the N-glycosylation pathway, where it catalyzes the transfer of a glycan from a lipid-linked oligosaccharide (LLO) to an acceptor asparagine within the conserved sequon N-X-T/S. A previous structure of a ternary complex of bacterial single subunit O...

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Published in:Sci Rep
Main Authors: Napiórkowska, Maja, Boilevin, Jérémy, Darbre, Tamis, Reymond, Jean-Louis, Locher, Kaspar P.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215017/
https://ncbi.nlm.nih.gov/pubmed/30389987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34534-0
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