The quest for the cure: The science and stories behind the next generation of medicines

Por Lo, Donald C.
Publicado em 2011

Development of a low-pressure microtargeting biolistic device for transfection of retinal explants

Por Christianson, Melissa G., Lo, Donald C.
Publicado em 2011

Differential roles of Aβ processing in hypoxia-induced axonal damage

Por Christianson, Melissa G., Lo, Donald C.
Publicado no Neurobiol Dis (2015)

Experimental Models for Identifying Modifiers of Polyglutamine-Induced Aggregation and Neurodegeneration

Por Calamini, Barbara, Lo, Donald C., Kaltenbach, Linda S.
Publicado em 2013

Neurotrophin regulation of ionic currents and cell size depends on cell context

Por Sherwood, Nina Tang, Lesser, Steven S., Lo, Donald C.
Publicado em 1997

High Throughput Screening for Neurodegeneration and Complex Disease Phenotypes

Por Varma, Hemant, Lo, Donald C., Stockwell, Brent R.
Publicado em 2008

Activated microglia proliferate at neurites of mutant huntingtin-expressing neurons

Por Kraft, Andrew D., Kaltenbach, Linda S., Lo, Donald C., Harry, G. Jean
Publicado em 2011

Reduction of facial wrinkles by hydrolyzed water-soluble egg membrane associated with reduction of free radical stress and support of matrix production by dermal fibroblasts

Por Jensen, Gitte S, Shah, Bijal, Holtz, Robert, Patel, Ashok, Lo, Donald C
Publicado no Clin Cosmet Investig Dermatol (2016)

Neuronal IL-4Rα modulates neuronal apoptosis and cell viability during the acute phases of cerebral ischemia

Por Lee, Han Kyu, Koh, Sehwon, Lo, Donald C., Marchuk, Douglas A.
Publicado no FEBS J (2018)

Protein aggregation can inhibit clathrin-mediated endocytosis by chaperone competition

Por Yu, Anan, Shibata, Yoko, Shah, Bijal, Calamini, Barbara, Lo, Donald C., Morimoto, Richard I.
Publicado em 2014

Natural allelic variation of the IL-21 receptor modulates ischemic stroke infarct volume

Por Lee, Han Kyu, Keum, Sehoon, Sheng, Huaxin, Warner, David S., Lo, Donald C., Marchuk, Douglas A.
Publicado no J Clin Invest (2016)

Intrabodies Binding the Proline-Rich Domains of Mutant Huntingtin Increase Its Turnover and Reduce Neurotoxicity

Por Southwell, Amber L., Khoshnan, Ali, Dunn, Denise E., Bugg, Charles W., Lo, Donald C., Patterson, Paul H.
Publicado em 2008

Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins

Por Hoffstrom, Benjamin G., Kaplan, Anna, Letso, Reka, Schmid, Ralf, Turmel, Gregory J., Lo, Donald C., Stockwell, Brent R.
Publicado em 2010

Neuroprotective Effects of Annexin A1 Tripeptide after Deep Hypothermic Circulatory Arrest in Rats

Por Zhang, Zhiquan, Ma, Qing, Shah, Bijal, Mackensen, G. Burkhard, Lo, Donald C., Mathew, Joseph P., Podgoreanu, Mihai V., Terrando, Niccolò
Publicado no Front Immunol (2017)

Cardiac glycosides provide neuroprotection against ischemic stroke: Discovery by a brain slice-based compound screening platform

Por Wang, James K. T., Portbury, Stuart, Thomas, Mary Beth, Barney, Shawn, Ricca, Daniel J., Morris, Dexter L., Warner, David S., Lo, Donald C.
Publicado em 2006

BDNF Mediates Neuroprotection against Oxygen-Glucose Deprivation by the Cardiac Glycoside Oleandrin

Por Van Kanegan, Michael J., He, Dong Ning, Dunn, Denise E., Yang, Peiying, Newman, Robert A., West, Anne E., Lo, Donald C.
Publicado em 2014

Perturbation with Intrabodies Reveals That Calpain Cleavage Is Required for Degradation of Huntingtin Exon 1

Por Southwell, Amber L., Bugg, Charles W., Kaltenbach, Linda S., Dunn, Denise, Butland, Stefanie, Weiss, Andreas, Paganetti, Paolo, Lo, Donald C., Patterson, Paul H.
Publicado em 2011

Small molecule-induced oxidation of protein disulfide isomerase is neuroprotective

Por Kaplan, Anna, Gaschler, Michael M., Dunn, Denise E., Colligan, Ryan, Brown, Lewis M., Palmer, Arthur G., Lo, Donald C., Stockwell, Brent R.
Publicado no Proc Natl Acad Sci U S A (2015)

IKK/NF-κB signaling contributes to glioblastoma stem cell maintenance

Por Rinkenbaugh, Amanda L., Cogswell, Patricia C., Calamini, Barbara, Dunn, Denise E., Persson, Anders I., Weiss, William A., Lo, Donald C., Baldwin, Albert S.
Publicado no Oncotarget (2016)

Structure-activity relationship study of EphB3 receptor tyrosine kinase inhibitors

Por Qiao, Lixin, Choi, Sungwoon, Case, April, Gainer, Thomas G., Seyb, Kathleen, Glicksman, Marcie A., Lo, Donald C., Stein, Ross L., Cuny, Gregory D.
Publicado em 2009