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Cardiac glycosides provide neuroprotection against ischemic stroke: Discovery by a brain slice-based compound screening platform
We report here the results of a chemical genetic screen using small molecules with known pharmacologies coupled with a cortical brain slice-based model for ischemic stroke. We identified a small-molecule compound not previously appreciated to have neuroprotective action in ischemic stroke, the cardi...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1481664/ https://ncbi.nlm.nih.gov/pubmed/16793926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600930103 |
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