Loading...

Experimental Models for Identifying Modifiers of Polyglutamine-Induced Aggregation and Neurodegeneration

Huntington’s disease (HD) typifies a class of inherited neurodegenerative disorders in which a CAG expansion in a single gene leads to an extended polyglutamine tract and misfolding of the expressed protein, driving cumulative neural dysfunction and degeneration. HD is invariably fatal with symptoms...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Calamini, Barbara, Lo, Donald C., Kaltenbach, Linda S.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701774/
https://ncbi.nlm.nih.gov/pubmed/23700210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-013-0195-4
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!