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Natural allelic variation of the IL-21 receptor modulates ischemic stroke infarct volume

Risk for ischemic stroke has a strong genetic basis, but heritable factors also contribute to the extent of damage after a stroke has occurred. We previously identified a locus on distal mouse chromosome 7 that contributes over 50% of the variation in postischemic cerebral infarct volume observed be...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Lee, Han Kyu, Keum, Sehoon, Sheng, Huaxin, Warner, David S., Lo, Donald C., Marchuk, Douglas A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966306/
https://ncbi.nlm.nih.gov/pubmed/27400126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI84491
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