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Protein aggregation can inhibit clathrin-mediated endocytosis by chaperone competition
Protein conformational diseases exhibit complex pathologies linked to numerous molecular defects. Aggregation of a disease-associated protein causes the misfolding and aggregation of other proteins, but how this interferes with diverse cellular pathways is unclear. Here, we show that aggregation of...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3992642/ https://ncbi.nlm.nih.gov/pubmed/24706768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321811111 |
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