EPEN-53. C11orf95-RELA REPROGRAMS 3D EPIGENOME IN SUPRATENTORIAL EPENDYMOMA

Por Zhu, Jacqueline Jufen, Jillette, Nathaniel, Li, Xiao-Nan, Cheng, Albert, Lau, Ching
Publicado no Neuro Oncol (2020)

C11orf95-RELA reprograms 3D epigenome in supratentorial ependymoma

Por Zhu, Jacqueline Jufen, Jillette, Nathaniel, Li, Xiao-Nan, Cheng, Albert Wu, Lau, Ching C.
Publicado no Acta Neuropathol (2020)

Inhibition of Mutated Isocitrate Dehydrogenase 1 in Cancer

Por Wu, Fangrui, Cheng, Gang, Yao, Yuan, Kogiso, Mari, Jiang, Hong, Li, Xiao-Nan, Song, Yongcheng
Publicado no Med Chem (2018)

Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2-thiohydantoin compounds

Por Wu, Fangrui, Jiang, Hong, Zheng, Baisong, Kogiso, Mari, Yao, Yuan, Zhou, Chao, Li, Xiao-Nan, Song, Yongcheng
Publicado no J Med Chem (2015)

TMOD-07. EVALUATING THE POWER OF PATIENT TUMOR-DERIVED ORTHOTOPIC XENOGRAFT (PDOX) MODELS OF PEDIATRIC BRAIN TUMORS TO PREDICT DRUG RESPONSES IN HUMANS

Por Injac, Sarah, Du, Yuchen, Kogiso, Mari, Braun, Frank, Qi, Lin, Lindsay, Holly, Zhao, Sibo, Li, Xiao-Nan
Publicado no Neuro Oncol (2017)

Resveratrol protects against oxidative stress by activating the Keap-1/Nrf2 antioxidant defense system in obese-asthmatic rats

Por Li, Xiao-Nan, Ma, Lu-Yi, Ji, Hong, Qin, Yuan-Hua, Jin, Shan-Shan, Xu, Li-Xin
Publicado no Exp Ther Med (2018)

HG-06 INHIBITION OF EPIGENETIC REGULATION AS A THERAPY FOR PEDIATRIC HIGH GRADE GLIOMA

Por Dombrowski, Stephen, Abou-Antoun, Thamara, Mack, Stephen, Li, Xiao-Nan, Houghton, Peter, Bigner, Darell, Rich, Jeremy, Recinos, Violette
Publicado no Neuro Oncol (2015)

HG-22 TREATMENT OF INTRA-BRAIN STEM XENOGRAFT MOUSE MODELS OF DIPG WITH COMBINED RADIATION AND ONCOLYTIC VIRAL THERAPY

Por Du, Yuchen, Zhang, Huiyuan, Qi, Lin, Lindsay, Holly, Kogiso, Mari, Zhao, Sibo, Braun, Frank K., Li, Xiao-Nan
Publicado no Neuro Oncol (2016)

PDTM-07. SYSTEMATIC DRUG IDENTIFIES DIGOXIN AS A DRUG THAT PROLONGS SURVIVAL IN PDOX MODELS OF GROUPS 3 AND 4 MEDULLOBLASTOMA AT CLINICALLY RELEVANT DOSES

Por Injac, Sarah, Huang, Lei, Zhao, Hong, Qi, Lin, Kogiso, Mari, Man, Chris, Li, Xiao-Nan, Lau, Ching, Wong, Stephen
Publicado no Neuro Oncol (2017)

PDTM-17. IDENTIFICATION OF HUMAN PEDIATRIC BRAIN TUMORS CELLS IN PATIENT DERIVED ORTHOTOPIC XENOGRAFT MOUSE MODELS BY USING SPECIES-SPECIFIC PTGER2 GENE qPCR

Por Braun, Frank, Kogiso, Mari, Qi, Lin, Zhang, Huiyuan, Du, Yuchen, Lindsay, Holly, Zhao, Sibo, Injac, Sarah, Li, Xiao-Nan
Publicado no Neuro Oncol (2017)

PCLN-02. EVALUATING THE POWER OF PATIENT TUMOR-DERIVED ORTHOTOPIC XENOGRAFT (PDOX) MODELS OF PEDIATRIC BRAIN TUMORS TO PREDICT DRUG RESPONSES IN HUMANS

Por Injac, Sarah, Du, Yuchen, Kogiso, Mari, Braun, Frank, Zhang, Huiyuan, Qi, Lin, Lindsay, Holly, Zhao, Sibo, Li, Xiao-nan
Publicado no Neuro Oncol (2018)

MBRS-56. SYSTEMATIC DRUG REPURPOSING IDENTIFIES DIGOXIN AS A DRUG THAT PROLONGS SURVIVAL IN PDOX MODELS OF GROUPS 3 AND 4 MEDULLOBLASTOMA AT CLINICALLY RELEVANT DOSES

Por Injac, Sarah, Huang, Lei, Zhao, Hong, Lin, Qi, Kogiso, Mari, Man, Chris, Li, Xiao-nan, Wong, Stephen, Lau, Ching
Publicado no Neuro Oncol (2018)

TMOD-13. MAXIMIZING THE POWER OF PATIENT TUMOR-DERIVED ORTHOTOPIC XENOGRAFT (PDOX) MODELS OF PEDIATRIC BRAIN TUMORS TO PREDICT DRUG RESPONSES IN HUMANS

Por Injac, Sarah, Du, Yuchen, Kogiso, Mari, Braun, Frank, Zhang, Huiyuan, Qi, Lin, Lindsay, Holly, Zhao, Sibo, Li, Xiao-nan
Publicado no Neuro Oncol (2019)

Biogenesis of Short Intronic Repeat 27-Nucleotide Small RNA from Endothelial Nitric-oxide Synthase Gene

Por Zhang, Ming-Xiang, Zhang, Cheng, Shen, Ying H., Wang, Jian, Li, Xiao Nan, Zhang, Yun, Coselli, Joseph, Wang, Xing Li
Publicado em 2008

Polycomb group gene BMI1 controls invasion of medulloblastoma cells and inhibits BMP-regulated cell adhesion

Por Merve, Ashirwad, Dubuc, Adrian M, Zhang, Xinyu, Remke, Marc, Baxter, Patricia A, Li, Xiao-Nan, Taylor, Michael D, Marino, Silvia
Publicado em 2014

Glycan Engagement Dictates Hydrocephalus Induction by Serotype 1 Reovirus

Por Stencel-Baerenwald, Jennifer, Reiss, Kerstin, Blaum, Bärbel S., Colvin, Daniel, Li, Xiao-Nan, Abel, Ty, Boyd, Kelli, Stehle, Thilo, Dermody, Terence S.
Publicado no mBio (2015)

PDTM-22. A C19MC-LIN28A-MYCN ONCOGENIC CIRCUIT DRIVEN BY HIJACKED SUPER-ENHANCERS IS A DISTINCT THERAPEUTIC VULNERABILITY IN ETMRS – A LETHAL BRAIN TUMOR

Por Mumal, Iqra, Sin-Chan, Patrick, Suwal, Tannu, Singh, Irtisha, Li, Xiao-Nan, Lin, Charles, Rich, Jeremy, Mack, Stephen, Huang, Annie
Publicado no Neuro Oncol (2019)

TBIO-02. IMMUNE PROFILING OF RARE EMBRYONAL BRAIN TUMORS REVEAL EVIDENCE OF DYSREGULATED INTERFERON SIGNALLING AS A POTENTIAL DETERMINANT OF IMMUNOLOGICAL HETEROGENEITY

Por Popovski, Dean, Yao, Fupan, Bondoc, Andrew, Al-Karmi, Salma, Ho, Ben, Lindsay, Holly, Li, Xiao-Nan, Rutka, James, Huang, Annie
Publicado no Neuro Oncol (2020)

TMOD-41. TWO NOVEL SETS OF PATIENT DERIVED ORTHOTOPIC XENOGRAFT MOUSE MODELS (PDOX) ESTABLISHED FROM MATCHING PRIMARY AND RECURRENT PEDIATRIC BRAIN TUMORS

Por Du, Yuchen, Braun, Frank, Zhang, Huiyuan, Qi, Lin, Lindsay, Holly, Kogiso, Mari, Zhao, Sibo, Kool, Marcel, Stephan, Clifford, Li, Xiao-Nan
Publicado no Neuro Oncol (2017)

EPEN-13. NOVEL LSD-1 INHIBITOR VALIDATION IN NEWLY ESTABLISHED PFA EPENDYMOMA PATIENT-DERIVED ORTHOTOPIC XENOGRAFT (PDOX) MODELS

Por Zhao, Sibo, Zhang, Huiyuan, Qi, Lin, Lindsay, Holly, Du, Yuchen, Braun, Frank, Kogiso, Mari, Injac, Sarah, Song, Yongcheng, Li, Xiao-Nan
Publicado no Neuro Oncol (2018)