PCLN-02. EVALUATING THE POWER OF PATIENT TUMOR-DERIVED ORTHOTOPIC XENOGRAFT (PDOX) MODELS OF PEDIATRIC BRAIN TUMORS TO PREDICT DRUG RESPONSES IN HUMANS

Brain tumors are the leading cause of cancer-related death in children. A major hurdle for clinical drug development is the lack of model systems that can accurately predict drug responses in human patients. To address this issue, our lab has established a large panel (>80) of orthotopic xenograf...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Injac, Sarah, Du, Yuchen, Kogiso, Mari, Braun, Frank, Zhang, Huiyuan, Qi, Lin, Lindsay, Holly, Zhao, Sibo, Li, Xiao-nan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012078/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.571
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