TMOD-13. MAXIMIZING THE POWER OF PATIENT TUMOR-DERIVED ORTHOTOPIC XENOGRAFT (PDOX) MODELS OF PEDIATRIC BRAIN TUMORS TO PREDICT DRUG RESPONSES IN HUMANS

Brain tumors are the leading cause of cancer-related death in children. A major challenge in the development of new therapies is the failure of many model systems to accurately predict drug responses patients. We identified two major weakness common to the majority of available models of pediatric b...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Injac, Sarah, Du, Yuchen, Kogiso, Mari, Braun, Frank, Zhang, Huiyuan, Qi, Lin, Lindsay, Holly, Zhao, Sibo, Li, Xiao-nan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Pediatric Brain Tumor Models
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477192/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.250
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