Caricamento...
Inhibition of Mutated Isocitrate Dehydrogenase 1 in Cancer
BACKGROUND: R132H mutation of isocitrate dehydrogenase 1 (IDH1) are found in ~75% of low-grade gliomas and secondary glioblastomas as well as in several other types of cancer. More chemotypes of inhibitors of IDH1(R132H) are therefore needed. OBJECTIVE: To develop a new class of IDH1(R132H) inhibito...
Salvato in:
| Pubblicato in: | Med Chem |
|---|---|
| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6205205/ https://ncbi.nlm.nih.gov/pubmed/29792149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1573406414666180524093659 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|