Human Cd25(+)Cd4(+) T Regulatory Cells Suppress Naive and Memory T Cell Proliferation and Can Be Expanded in Vitro without Loss of Function

Por Levings, Megan K., Sangregorio, Romina, Roncarolo, Maria-Grazia
Publicado em 2001

Differentiation of T Regulatory Cells by Immature Dendritic Cells

Por Roncarolo, Maria-Grazia, Levings, Megan K., Traversari, Catia
Publicado em 2001

The Role of the PI3K Signaling Pathway in CD4(+) T Cell Differentiation and Function

Por Han, Jonathan M., Patterson, Scott J., Levings, Megan K.
Publicado em 2012

The Environment of Regulatory T Cell Biology: Cytokines, Metabolites, and the Microbiome

Por Hoeppli, Romy E., Wu, Dan, Cook, Laura, Levings, Megan K.
Publicado no Front Immunol (2015)

Moving to tolerance: Clinical Application of T regulatory cells

Por McMurchy, Alicia N., Bushell, Andrew, Levings, Megan K., Wood, Kathryn J.
Publicado em 2011

The role of T-regulatory cells and Toll-like receptors in the pathogenesis of human inflammatory bowel disease

Por Himmel, Megan E, Hardenberg, Gijs, Piccirillo, Ciriaco A, Steiner, Theodore S, Levings, Megan K
Publicado em 2008

TH17 Cells in Autoimmunity and Immunodeficiency: Protective or Pathogenic?

Por Marwaha, Ashish K., Leung, Nicole J., McMurchy, Alicia N., Levings, Megan K.
Publicado em 2012

Regulatory T-cell therapy for inflammatory bowel disease: more questions than answers

Por Himmel, Megan E, Yao, Yu, Orban, Paul C, Steiner, Theodore S, Levings, Megan K
Publicado em 2012

SHIP-Deficient Dendritic Cells, Unlike Wild Type Dendritic Cells, Suppress T Cell Proliferation via a Nitric Oxide-Independent Mechanism

Por Antignano, Frann, Hamilton, Melisa, Patterson, Scott, Ho, Victor, Cohen, Carla, Levings, Megan K., Krystal, Gerald
Publicado em 2011

Human CD25(+)CD4(+) T Suppressor Cell Clones Produce Transforming Growth Factor β, but not Interleukin 10, and Are Distinct from Type 1 T Regulatory Cells

Por Levings, Megan K., Sangregorio, Romina, Sartirana, Claudia, Moschin, Anna Lisa, Battaglia, Manuela, Orban, Paul C., Roncarolo, Maria-Grazia
Publicado em 2002

Natural killer T cells constitutively expressing the interleukin-2 receptor α chain early in life are primed to respond to lower antigenic stimulation

Por Ladd, Mihoko, Sharma, Ashish, Huang, Qing, Wang, Adele Y, Xu, Lixin, Genowati, Indira, Levings, Megan K, Lavoie, Pascal M
Publicado em 2010

PHLPP regulates the development, function and molecular signaling pathways of T regulatory cells()

Por Patterson, Scott, Han, Jonathan, Garcia, Rosa, Assi, Kirin, Gao, Tianyan, O'Neill, Audrey, Newton, Alexandra C., Levings, Megan K.
Publicado em 2011

Inflammation-Driven Reprogramming of CD4(+)Foxp3(+) Regulatory T Cells into Pathogenic Th1/Th17 T Effectors Is Abrogated by mTOR Inhibition in vivo

Por Yurchenko, Ekaterina, Shio, Marina T., Huang, Tony C., Da Silva Martins, Maria, Szyf, Moshe, Levings, Megan K., Olivier, Martin, Piccirillo, Ciriaco A.
Publicado em 2012

Alloantigen-specific regulatory T cells generated with a chimeric antigen receptor

Por MacDonald, Katherine G., Hoeppli, Romy E., Huang, Qing, Gillies, Jana, Luciani, Dan S., Orban, Paul C., Broady, Raewyn, Levings, Megan K.
Publicado no J Clin Invest (2016)

Restimulation After Cryopreservation and Thawing Preserves the Phenotype and Function of Expanded Baboon Regulatory T Cells

Por Weiner, Joshua, Duran-Struuck, Raimon, Zitsman, Jonah, Buhler, Leo, Sondermeijer, Hugo, McMurchy, Alicia N., Levings, Megan K., Sykes, Megan, Griesemer, Adam
Publicado no Transplant Direct (2015)

The role of 2 FOXP3 isoforms in the generation of human CD4(+) Tregs

Por Allan, Sarah E., Passerini, Laura, Bacchetta, Rosa, Crellin, Natasha, Dai, Minyue, Orban, Paul C., Ziegler, Steven F., Roncarolo, Maria Grazia, Levings, Megan K.
Publicado em 2005

Prevention of murine autoimmune diabetes by CCL22-mediated Treg recruitment to the pancreatic islets

Por Montane, Joel, Bischoff, Loraine, Soukhatcheva, Galina, Dai, Derek L., Hardenberg, Gijs, Levings, Megan K., Orban, Paul C., Kieffer, Timothy J., Tan, Rusung, Verchere, C. Bruce
Publicado em 2011

T regulatory cell chemokine production mediates pathogenic T cell attraction and suppression

Por Patterson, Scott J., Pesenacker, Anne M., Wang, Adele Y., Gillies, Jana, Mojibian, Majid, Morishita, Kim, Tan, Rusung, Kieffer, Timothy J., Verchere, C. Bruce, Panagiotopoulos, Constadina, Levings, Megan K.
Publicado no J Clin Invest (2016)

Defective regulatory and effector T cell functions in patients with FOXP3 mutations

Por Bacchetta, Rosa, Passerini, Laura, Gambineri, Eleonora, Dai, Minyue, Allan, Sarah E., Perroni, Lucia, Dagna-Bricarelli, Franca, Sartirana, Claudia, Matthes-Martin, Susanne, Lawitschka, Anita, Azzari, Chiara, Ziegler, Steven F., Levings, Megan K., Roncarolo, Maria Grazia
Publicado em 2006

Active vitamin D (1,25-dihydroxyvitamin D(3)) increases host susceptibility to Citrobacter rodentium by suppressing mucosal Th17 responses

Por Ryz, Natasha R., Patterson, Scott J., Zhang, Yiqun, Ma, Caixia, Huang, Tina, Bhinder, Ganive, Wu, Xiujuan, Chan, Justin, Glesby, Alexa, Sham, Ho Pan, Dutz, Jan P., Levings, Megan K., Jacobson, Kevan, Vallance, Bruce A.
Publicado em 2012