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The role of 2 FOXP3 isoforms in the generation of human CD4(+) Tregs

Little is known about the molecules that control the development and function of CD4(+)CD25(+) Tregs. Recently, it was shown that the transcription factor FOXP3 is necessary and sufficient for the generation of CD4(+)CD25(+) Tregs in mice. We investigated the capacity of FOXP3 to drive the generatio...

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Detalhes bibliográficos
Main Authors: Allan, Sarah E., Passerini, Laura, Bacchetta, Rosa, Crellin, Natasha, Dai, Minyue, Orban, Paul C., Ziegler, Steven F., Roncarolo, Maria Grazia, Levings, Megan K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1242190/
https://ncbi.nlm.nih.gov/pubmed/16211090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24685
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