Natural killer T cells constitutively expressing the interleukin-2 receptor α chain early in life are primed to respond to lower antigenic stimulation

Invariant natural killer T (iNKT) cells are known to constitutively express the high affinity interlukin-2 receptor α chain (CD25) in neonates, but the functional consequence of this phenotype is unknown. Here, we show that high numbers of CD25-expressing iNKT cells are present early in gestation an...

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Detalhes bibliográficos
Main Authors: Ladd, Mihoko, Sharma, Ashish, Huang, Qing, Wang, Adele Y, Xu, Lixin, Genowati, Indira, Levings, Megan K, Lavoie, Pascal M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967274/
https://ncbi.nlm.nih.gov/pubmed/20545784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03304.x
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