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Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis
Differentiation and homeostasis of natural killer (NK) cells relies on common gamma-chain (γc)-dependent cytokines, in particular IL-15. Consequently, NK cells do not develop in mice with targeted γc deletion. Herein we identify an alternative pathway of NK-cell development driven by the proinflamma...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5172358/ https://ncbi.nlm.nih.gov/pubmed/27982126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13708 |
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