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Prevention of murine autoimmune diabetes by CCL22-mediated Treg recruitment to the pancreatic islets
Type 1 diabetes is characterized by destruction of insulin-producing β cells in the pancreatic islets by effector T cells. Tregs, defined by the markers CD4 and FoxP3, regulate immune responses by suppressing effector T cells and are recruited to sites of action by the chemokine CCL22. Here, we demo...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3148722/ https://ncbi.nlm.nih.gov/pubmed/21737880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43048 |
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