SHIP-Deficient Dendritic Cells, Unlike Wild Type Dendritic Cells, Suppress T Cell Proliferation via a Nitric Oxide-Independent Mechanism

BACKGROUND: Dendritic cells (DCs) not only play a crucial role in activating immune cells but also suppressing them. We recently investigated SHIP's role in murine DCs in terms of immune cell activation and found that TLR agonist-stimulated SHIP−/− GM-CSF-derived DCs (GM-DCs) were far less capa...

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Bibliografiske detaljer
Main Authors: Antignano, Frann, Hamilton, Melisa, Patterson, Scott, Ho, Victor, Cohen, Carla, Levings, Megan K., Krystal, Gerald
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130768/
https://ncbi.nlm.nih.gov/pubmed/21755007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021893
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