MyD88-Dependent SHIP1 Regulates Proinflammatory Signaling Pathways in Dendritic Cells after Monophosphoryl Lipid A Stimulation of TLR4

We previously showed that monophosphoryl lipid A (MLA) activates TLR4 in dendritic cells (DCs) in a Toll/IL-1R domain-containing adaptor inducing IFN-β (TRIF)–biased manner: MLA produced from Salmonella minnesota Re595 induced signaling events and expression of gene products that were primarily TRIF...

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Detalhes bibliográficos
Main Authors: Cekic, Caglar, Casella, Carolyn R., Sag, Duygu, Antignano, Frann, Kolb, Joseph, Suttles, Jill, Hughes, Michael R., Krystal, Gerald, Mitchell, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249415/
https://ncbi.nlm.nih.gov/pubmed/21339365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001034
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