SHIP prevents lipopolysaccharide from triggering an antiviral response in mice

Gram-negative bacterial infections, unlike viral infections, do not typically protect against subsequent viral infections. This is puzzling given that lipopolysaccharide (LPS) and double-stranded (ds) RNA both activate the TIR domain–containing adaptor-inducing interferon β (TRIF) pathway and, thus,...

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Main Authors: Sly, Laura M., Hamilton, Melisa J., Kuroda, Etsushi, Ho, Victor W., Antignano, Frann L., Omeis, Stephanie L., van Netten-Thomas, Christina J., Wong, Dana, Brugger, Hayley K., Williams, Olusegun, Feldman, Morris E., Houseman, Benjamin T., Fiedler, Dorothea, Shokat, Kevan M., Krystal, Gerald
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2009
Teme:
Immunobiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662641/
https://ncbi.nlm.nih.gov/pubmed/19139077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-06-166082
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