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Activity of the p110-α subunit of phosphatidylinositol-3-kinase is required for activation of epithelial sodium transport

The pathways implicated in the control of epithelial Na(+) channel (ENaC)-dependent Na(+) transport in renal collecting duct cells share substantial parallels with those implicated in insulin-regulated glucose metabolism. Notably, both are inhibited by wortmannin and LY294002 and signal through phos...

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Main Authors: Wang, Jian, Knight, Zachary A., Fiedler, Dorothea, Williams, Olusegun, Shokat, Kevan M., Pearce, David
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536874/
https://ncbi.nlm.nih.gov/pubmed/18653476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90348.2008
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