TMPRSS4-dependent activation of the epithelial sodium channel requires cleavage of the γ-subunit distal to the furin cleavage site

The epithelial sodium channel (ENaC) is activated by a unique mechanism, whereby inhibitory tracts are released by proteolytic cleavage within the extracellular loops of two of its three homologous subunits. While cleavage by furin within the biosynthetic pathway releases one inhibitory tract from t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Passero, Christopher J., Mueller, Gunhild M., Myerburg, Michael M., Carattino, Marcelo D., Hughey, Rebecca P., Kleyman, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Call for Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251344/
https://ncbi.nlm.nih.gov/pubmed/21993886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00330.2011
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados