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Plasmin Activates Epithelial Na(+) Channels by Cleaving the γ Subunit
Proteolytic processing of epithelial sodium channel (ENaC) subunits occurs as channels mature within the biosynthetic pathway. The proteolytic processing events of the α and γ subunits are associated with channel activation. Furin cleaves the α subunit ectodomain at two sites, releasing an inhibitor...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2605981/ https://ncbi.nlm.nih.gov/pubmed/18981180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805676200 |
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