Systematic Identification of Spontaneous Preterm Birth-Associated RNA Transcripts in Maternal Plasma

por Chim, Stephen S. C., Lee, Wing S., Ting, Yuen H., Chan, Oi K., Lee, Shara W. Y., Leung, Tak Y.
Publicado em 2012

Epigenetic-Genetic Chromosome Dosage Approach for Fetal Trisomy 21 Detection Using an Autosomal Genetic Reference Marker

por Tong, Yu K., Chiu, Rossa W. K., Akolekar, Ranjit, Leung, Tak Y., Lau, Tze K., Nicolaides, Kypros H., Lo, Y. M. Dennis
Publicado em 2010

Maternal Plasma Fetal DNA Fractions in Pregnancies with Low and High Risks for Fetal Chromosomal Aneuploidies

por Hudecova, Irena, Sahota, Daljit, Heung, Macy M. S., Jin, Yongjie, Lee, Wing S., Leung, Tak Y., Lo, Yuk Ming Dennis, Chiu, Rossa W.K.
Publicado em 2014

Noninvasive Prenatal Diagnosis of Fetal Trisomy 21 by Allelic Ratio Analysis Using Targeted Massively Parallel Sequencing of Maternal Plasma DNA

por Liao, Gary J. W., Chan, K. C. Allen, Jiang, Peiyong, Sun, Hao, Leung, Tak Y., Chiu, Rossa W. K., Lo, Y. M. Dennis
Publicado em 2012

Placenta-Derived Fetal Specific mRNA Is More Readily Detectable in Maternal Plasma than in Whole Blood

por Heung, Macy M. S., Jin, Shengnan, Tsui, Nancy B. Y., Ding, Chunming, Leung, Tak Y., Lau, Tze K., Chiu, Rossa W. K., Lo, Y. M. Dennis
Publicado em 2009

High Resolution Size Analysis of Fetal DNA in the Urine of Pregnant Women by Paired-End Massively Parallel Sequencing

por Tsui, Nancy B. Y., Jiang, Peiyong, Chow, Katherine C. K., Su, Xiaoxi, Leung, Tak Y., Sun, Hao, Chan, K. C. Allen, Chiu, Rossa W. K., Lo, Y. M. Dennis
Publicado em 2012

Identification and characterization of extrachromosomal circular DNA in maternal plasma

por Sin, Sarah T. K., Jiang, Peiyong, Deng, Jiaen, Ji, Lu, Cheng, Suk Hang, Dutta, Anindya, Leung, Tak Y., Chan, K. C. Allen, Chiu, Rossa W. K., Lo, Y. M. Dennis
Publicado no Proc Natl Acad Sci U S A (2020)

FetalQuant(SD): accurate quantification of fetal DNA fraction by shallow-depth sequencing of maternal plasma DNA

por Jiang, Peiyong, Peng, Xianlu, Su, Xiaoxi, Sun, Kun, Yu, Stephanie C Y, Chu, Weng In, Leung, Tak Y, Sun, Hao, Chiu, Rossa W K, Lo, Yuk Ming Dennis, Chan, Kwan Chee Allen
Publicado no NPJ Genom Med (2016)

Size-tagged preferred ends in maternal plasma DNA shed light on the production mechanism and show utility in noninvasive prenatal testing

por Sun, Kun, Jiang, Peiyong, Wong, Ada I. C., Cheng, Yvonne K. Y., Cheng, Suk Hang, Zhang, Haiqiang, Chan, K. C. Allen, Leung, Tak Y., Chiu, Rossa W. K., Lo, Y. M. Dennis
Publicado no Proc Natl Acad Sci U S A (2018)

Second generation noninvasive fetal genome analysis reveals de novo mutations, single-base parental inheritance, and preferred DNA ends

por Chan, K. C. Allen, Jiang, Peiyong, Sun, Kun, Cheng, Yvonne K. Y., Tong, Yu K., Cheng, Suk Hang, Wong, Ada I. C., Hudecova, Irena, Leung, Tak Y., Chiu, Rossa W. K., Lo, Yuk Ming Dennis
Publicado no Proc Natl Acad Sci U S A (2016)

Digital PCR for the molecular detection of fetal chromosomal aneuploidy

por Lo, Y. M. Dennis, Lun, Fiona M. F., Chan, K. C. Allen, Tsui, Nancy B. Y., Chong, Ka C., Lau, Tze K., Leung, Tak Y., Zee, Benny C. Y., Cantor, Charles R., Chiu, Rossa W. K.
Publicado em 2007

Noninvasive Prenatal Molecular Karyotyping from Maternal Plasma

por Yu, Stephanie C. Y., Jiang, Peiyong, Choy, Kwong W., Chan, Kwan Chee Allen, Won, Hye-Sung, Leung, Wing C., Lau, Elizabeth T., Tang, Mary H. Y., Leung, Tak Y., Lo, Yuk Ming Dennis, Chiu, Rossa W. K.
Publicado em 2013

Genome-wide detection of cytosine methylation by single molecule real-time sequencing

por Tse, O. Y. Olivia, Jiang, Peiyong, Cheng, Suk Hang, Peng, Wenlei, Shang, Huimin, Wong, John, Chan, Stephen L., Poon, Liona C. Y., Leung, Tak Y., Chan, K. C. Allen, Chiu, Rossa W. K., Lo, Y. M. Dennis
Publicado no Proc Natl Acad Sci U S A (2021)

Systematic Identification of Placental Epigenetic Signatures for the Noninvasive Prenatal Detection of Edwards Syndrome

por Tsui, Dana W. Y., Lam, Y. M. Doris, Lee, Wing S., Leung, Tak Y., Lau, Tze K., Lau, Elizabeth T., Tang, Mary H. Y., Akolekar, Ranjit, Nicolaides, Kypros H., Chiu, Rossa W. K., Lo, Y. M. Dennis, Chim, Stephen S. C.
Publicado em 2010

Noninvasive prenatal diagnosis of monogenic diseases by digital size selection and relative mutation dosage on DNA in maternal plasma

por Lun, Fiona M. F., Tsui, Nancy B. Y., Chan, K. C. Allen, Leung, Tak Y., Lau, Tze K., Charoenkwan, Pimlak, Chow, Katherine C. K., Lo, Wyatt Y. W., Wanapirak, Chanane, Sanguansermsri, Torpong, Cantor, Charles R., Chiu, Rossa W. K., Lo, Y. M. Dennis
Publicado em 2008

Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma

por Chiu, Rossa W. K., Chan, K. C. Allen, Gao, Yuan, Lau, Virginia Y. M., Zheng, Wenli, Leung, Tak Y., Foo, Chris H. F., Xie, Bin, Tsui, Nancy B. Y., Lun, Fiona M. F., Zee, Benny C. Y., Lau, Tze K., Cantor, Charles R., Lo, Y. M. Dennis
Publicado em 2008

Applications of genetic-epigenetic tissue mapping for plasma DNA in prenatal testing, transplantation and oncology

por Gai, Wanxia, Zhou, Ze, Agbor-Enoh, Sean, Fan, Xiaodan, Lian, Sheng, Jiang, Peiyong, Cheng, Suk Hang, Wong, John, Chan, Stephen L, Jang, Moon Kyoo, Yang, Yanqin, Liang, Raymond HS, Chan, Wai Kong, Ma, Edmond SK, Leung, Tak Y, Chiu, Rossa WK, Valantine, Hannah, Chan, KC Allen, Lo, YM Dennis
Publicado no eLife (2021)

Size-based molecular diagnostics using plasma DNA for noninvasive prenatal testing

por Yu, Stephanie C. Y., Chan, K. C. Allen, Zheng, Yama W. L., Jiang, Peiyong, Liao, Gary J. W., Sun, Hao, Akolekar, Ranjit, Leung, Tak Y., Go, Attie T. J. I., van Vugt, John M. G., Minekawa, Ryoko, Oudejans, Cees B. M., Nicolaides, Kypros H., Chiu, Rossa W. K., Lo, Y. M. Dennis
Publicado em 2014

Detection and characterization of jagged ends of double-stranded DNA in plasma

por Jiang, Peiyong, Xie, Tingting, Ding, Spencer C., Zhou, Ze, Cheng, Suk Hang, Chan, Rebecca W.Y., Lee, Wing-Shan, Peng, Wenlei, Wong, John, Wong, Vincent W.S., Chan, Henry L.Y., Chan, Stephen L., Poon, Liona C.Y., Leung, Tak Y., Chan, K.C. Allen, Chiu, Rossa W.K., Lo, Y.M. Dennis
Publicado no Genome Res (2020)

Orientation-aware plasma cell-free DNA fragmentation analysis in open chromatin regions informs tissue of origin

por Sun, Kun, Jiang, Peiyong, Cheng, Suk Hang, Cheng, Timothy H.T., Wong, John, Wong, Vincent W.S., Ng, Simon S.M., Ma, Brigette B.Y., Leung, Tak Y., Chan, Stephen L., Mok, Tony S.K., Lai, Paul B.S., Chan, Henry L.Y., Sun, Hao, Chan, K.C. Allen, Chiu, Rossa W.K., Lo, Y.M. Dennis
Publicado no Genome Res (2019)