Applications of genetic-epigenetic tissue mapping for plasma DNA in prenatal testing, transplantation and oncology

We developed genetic-epigenetic tissue mapping (GETMap) to determine the tissue composition of plasma DNA carrying genetic variants not present in the constitutional genome through comparing their methylation profiles with relevant tissues. We validated this approach by showing that, in pregnant wom...

詳細記述

保存先:
書誌詳細
出版年:eLife
主要な著者: Gai, Wanxia, Zhou, Ze, Agbor-Enoh, Sean, Fan, Xiaodan, Lian, Sheng, Jiang, Peiyong, Cheng, Suk Hang, Wong, John, Chan, Stephen L, Jang, Moon Kyoo, Yang, Yanqin, Liang, Raymond HS, Chan, Wai Kong, Ma, Edmond SK, Leung, Tak Y, Chiu, Rossa WK, Valantine, Hannah, Chan, KC Allen, Lo, YM Dennis
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2021
主題:
Medicine
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7997656/
https://ncbi.nlm.nih.gov/pubmed/33752803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.64356
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