Applications of genetic-epigenetic tissue mapping for plasma DNA in prenatal testing, transplantation and oncology

We developed genetic-epigenetic tissue mapping (GETMap) to determine the tissue composition of plasma DNA carrying genetic variants not present in the constitutional genome through comparing their methylation profiles with relevant tissues. We validated this approach by showing that, in pregnant wom...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:eLife
Hlavní autoři: Gai, Wanxia, Zhou, Ze, Agbor-Enoh, Sean, Fan, Xiaodan, Lian, Sheng, Jiang, Peiyong, Cheng, Suk Hang, Wong, John, Chan, Stephen L, Jang, Moon Kyoo, Yang, Yanqin, Liang, Raymond HS, Chan, Wai Kong, Ma, Edmond SK, Leung, Tak Y, Chiu, Rossa WK, Valantine, Hannah, Chan, KC Allen, Lo, YM Dennis
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2021
Témata:
Medicine
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7997656/
https://ncbi.nlm.nih.gov/pubmed/33752803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.64356
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky