Enrichment of fetal and maternal long cell‐free DNA fragments from maternal plasma following DNA repair

OBJECTIVE: Cell‐free DNA (cfDNA) fragments in maternal plasma contain DNA damage and may negatively impact the sensitivity of noninvasive prenatal testing (NIPT). However, some of these DNA damages are potentially reparable. We aimed to recover these damaged cfDNA molecules using PreCR DNA repair mi...

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Detalles Bibliográficos
Publicado en:Prenat Diagn
Autores principales: Vong, Joaquim S.L., Jiang, Peiyong, Cheng, Suk‐Hang, Lee, Wing‐Shan, Tsang, Jason C.H., Leung, Tak‐Yeung, Chan, K.C. Allen, Chiu, Rossa W.K., Lo, Y.M. Dennis
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619283/
https://ncbi.nlm.nih.gov/pubmed/30575063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pd.5406
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