Enrichment of fetal and maternal long cell‐free DNA fragments from maternal plasma following DNA repair

OBJECTIVE: Cell‐free DNA (cfDNA) fragments in maternal plasma contain DNA damage and may negatively impact the sensitivity of noninvasive prenatal testing (NIPT). However, some of these DNA damages are potentially reparable. We aimed to recover these damaged cfDNA molecules using PreCR DNA repair mi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Prenat Diagn
Prif Awduron: Vong, Joaquim S.L., Jiang, Peiyong, Cheng, Suk‐Hang, Lee, Wing‐Shan, Tsang, Jason C.H., Leung, Tak‐Yeung, Chan, K.C. Allen, Chiu, Rossa W.K., Lo, Y.M. Dennis
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2019
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619283/
https://ncbi.nlm.nih.gov/pubmed/30575063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pd.5406
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