Enrichment of fetal and maternal long cell‐free DNA fragments from maternal plasma following DNA repair

OBJECTIVE: Cell‐free DNA (cfDNA) fragments in maternal plasma contain DNA damage and may negatively impact the sensitivity of noninvasive prenatal testing (NIPT). However, some of these DNA damages are potentially reparable. We aimed to recover these damaged cfDNA molecules using PreCR DNA repair mi...

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Detalhes bibliográficos
Publicado no:Prenat Diagn
Main Authors: Vong, Joaquim S.L., Jiang, Peiyong, Cheng, Suk‐Hang, Lee, Wing‐Shan, Tsang, Jason C.H., Leung, Tak‐Yeung, Chan, K.C. Allen, Chiu, Rossa W.K., Lo, Y.M. Dennis
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619283/
https://ncbi.nlm.nih.gov/pubmed/30575063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pd.5406
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