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Placenta-Derived Fetal Specific mRNA Is More Readily Detectable in Maternal Plasma than in Whole Blood

BACKGROUND: Placental mRNA was detected in maternal whole blood, raising the possibility of using maternal blood for noninvasive prenatal diagnosis. We investigated fetal mRNA detection in maternal whole blood and determined if it offered advantages over maternal plasma analysis. METHODOLOGY: The co...

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Detalhes bibliográficos
Main Authors: Heung, Macy M. S., Jin, Shengnan, Tsui, Nancy B. Y., Ding, Chunming, Leung, Tak Y., Lau, Tze K., Chiu, Rossa W. K., Lo, Y. M. Dennis
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690655/
https://ncbi.nlm.nih.gov/pubmed/19516908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005858
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