Placenta-Derived Fetal Specific mRNA Is More Readily Detectable in Maternal Plasma than in Whole Blood

BACKGROUND: Placental mRNA was detected in maternal whole blood, raising the possibility of using maternal blood for noninvasive prenatal diagnosis. We investigated fetal mRNA detection in maternal whole blood and determined if it offered advantages over maternal plasma analysis. METHODOLOGY: The co...

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Main Authors: Heung, Macy M. S., Jin, Shengnan, Tsui, Nancy B. Y., Ding, Chunming, Leung, Tak Y., Lau, Tze K., Chiu, Rossa W. K., Lo, Y. M. Dennis
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690655/
https://ncbi.nlm.nih.gov/pubmed/19516908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005858
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