Systematic Identification of Placental Epigenetic Signatures for the Noninvasive Prenatal Detection of Edwards Syndrome

BACKGROUND: Noninvasive prenatal diagnosis of fetal aneuploidy by maternal plasma analysis is challenging owing to the low fractional and absolute concentrations of fetal DNA in maternal plasma. Previously, we demonstrated for the first time that fetal DNA in maternal plasma could be specifically ta...

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Bibliografische gegevens
Hoofdauteurs: Tsui, Dana W. Y., Lam, Y. M. Doris, Lee, Wing S., Leung, Tak Y., Lau, Tze K., Lau, Elizabeth T., Tang, Mary H. Y., Akolekar, Ranjit, Nicolaides, Kypros H., Chiu, Rossa W. K., Lo, Y. M. Dennis, Chim, Stephen S. C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2010
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994810/
https://ncbi.nlm.nih.gov/pubmed/21152411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015069
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