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Systematic Identification of Placental Epigenetic Signatures for the Noninvasive Prenatal Detection of Edwards Syndrome

BACKGROUND: Noninvasive prenatal diagnosis of fetal aneuploidy by maternal plasma analysis is challenging owing to the low fractional and absolute concentrations of fetal DNA in maternal plasma. Previously, we demonstrated for the first time that fetal DNA in maternal plasma could be specifically ta...

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Bibliografiske detaljer
Main Authors: Tsui, Dana W. Y., Lam, Y. M. Doris, Lee, Wing S., Leung, Tak Y., Lau, Tze K., Lau, Elizabeth T., Tang, Mary H. Y., Akolekar, Ranjit, Nicolaides, Kypros H., Chiu, Rossa W. K., Lo, Y. M. Dennis, Chim, Stephen S. C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994810/
https://ncbi.nlm.nih.gov/pubmed/21152411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015069
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