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Systematic Identification of Placental Epigenetic Signatures for the Noninvasive Prenatal Detection of Edwards Syndrome

BACKGROUND: Noninvasive prenatal diagnosis of fetal aneuploidy by maternal plasma analysis is challenging owing to the low fractional and absolute concentrations of fetal DNA in maternal plasma. Previously, we demonstrated for the first time that fetal DNA in maternal plasma could be specifically ta...

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Autori principali: Tsui, Dana W. Y., Lam, Y. M. Doris, Lee, Wing S., Leung, Tak Y., Lau, Tze K., Lau, Elizabeth T., Tang, Mary H. Y., Akolekar, Ranjit, Nicolaides, Kypros H., Chiu, Rossa W. K., Lo, Y. M. Dennis, Chim, Stephen S. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994810/
https://ncbi.nlm.nih.gov/pubmed/21152411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015069
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