FetalQuant(SD): accurate quantification of fetal DNA fraction by shallow-depth sequencing of maternal plasma DNA

Noninvasive prenatal testing using massively parallel sequencing of maternal plasma DNA has been rapidly adopted in clinical use worldwide. Fetal DNA fraction in a maternal plasma sample is an important parameter for accurate interpretations of these tests. However, there is a lack of methods involv...

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Detalhes bibliográficos
Publicado no:NPJ Genom Med
Main Authors: Jiang, Peiyong, Peng, Xianlu, Su, Xiaoxi, Sun, Kun, Yu, Stephanie C Y, Chu, Weng In, Leung, Tak Y, Sun, Hao, Chiu, Rossa W K, Lo, Yuk Ming Dennis, Chan, Kwan Chee Allen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685300/
https://ncbi.nlm.nih.gov/pubmed/29263813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjgenmed.2016.13
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