The potential of apolipoprotein mimetic peptides in the treatment of atherosclerosis

Por Leman, Luke J.
Publicado no Clin Lipidol (2015)

Biomimetic Catalysis of Diketopiperazine and Dipeptide Synthesis

Por Huang, Zheng-Zheng, Leman, Luke J., Ghadiri, M. Reza
Publicado em 2008

Molecules that Mimic Apolipoprotein A-I: Potential Agents for Treating Atherosclerosis

Por Leman, Luke J., Maryanoff, Bruce E., Ghadiri, M. Reza
Publicado em 2013

Macrocyclic Peptoid–Peptide Hybrids as Inhibitors of Class I Histone Deacetylases

Por Olsen, Christian A., Montero, Ana, Leman, Luke J., Ghadiri, M. Reza
Publicado em 2012

Design of a DNA-programmed plasminogen activator

Por Mukherjee, Purba, Leman, Luke J., Griffin, John H., Ghadiri, M. Reza
Publicado no J Am Chem Soc (2018)

Discovery of HDAC Inhibitors That Lack an Active Site Zn(2+)-Binding Functional Group

Por Vickers, Chris J., Olsen, Christian A., Leman, Luke J., Ghadiri, M. Reza
Publicado em 2012

Functional and Mechanistic Analyses of Biomimetic Aminoacyl Transfer Reactions in de novo Designed Coiled Coil Peptides via Rational Active Site Engineering

Por Leman, Luke J., Weinberger, Dana A., Huang, Zheng-Zheng, Wilcoxen, Keith M., Ghadiri, M. Reza
Publicado em 2007

Biomimetic Catalysis of Intermodular Aminoacyl Transfer

Por Wilcoxen, Keith M., Leman, Luke J., Weinberger, Dana A., Huang, Zheng-Zheng, Ghadiri, M. Reza
Publicado em 2007

Mimicry of High-Density Lipoprotein: Functional Peptide–Lipid Nanoparticles Based on Multivalent Peptide Constructs

Por Zhao, Yannan, Imura, Tomohiro, Leman, Luke J., Curtiss, Linda K., Maryanoff, Bruce E., Ghadiri, M. Reza
Publicado em 2013

Coiled-Coils at the Edge of Configurational Heterogeneity. Structural Analyses of Parallel and Antiparallel Homotetrameric Coiled-Coils Reveal Configurational Sensitivity to a Sing...

Por Yadav, Maneesh K., Leman, Luke J., Price, Daniel J., Brooks, Charles L., Stout, C. David, Ghadiri, M. Reza
Publicado em 2006

In vivo efficacy of HDL-like nanolipid particles containing multivalent peptide mimetics of apolipoprotein A-I

Por Zhao, Yannan, Black, Audrey S., Bonnet, David J., Maryanoff, Bruce E., Curtiss, Linda K., Leman, Luke J., Ghadiri, M. Reza
Publicado em 2014

Self-Assembling Cyclic d,l-α-Peptides as Modulators of Plasma HDL Function. A Supramolecular Approach toward Antiatherosclerotic Agents

Por Zhao, Yannan, Leman, Luke J., Search, Debra J., Garcia, Ricardo A., Gordon, David A., Maryanoff, Bruce E., Ghadiri, M. Reza
Publicado no ACS Cent Sci (2017)

Structure Based Engineering of Internal Cavities in Coiled-Coil Peptides

Por Yadav, Maneesh K., Redman, James E., Leman, Luke J., Alvarez-Gutiérrez, Julietta M., Zhang, Yanming, Stout, C. David, Ghadiri, M. Reza
Publicado em 2005

Selective incorporation of proteinaceous over nonproteinaceous cationic amino acids in model prebiotic oligomerization reactions

Por Frenkel-Pinter, Moran, Haynes, Jay W., C, Martin, Petrov, Anton S., Burcar, Bradley T., Krishnamurthy, Ramanarayanan, Hud, Nicholas V., Leman, Luke J., Williams, Loren Dean
Publicado no Proc Natl Acad Sci U S A (2019)

Mutually stabilizing interactions between proto-peptides and RNA

Por Frenkel-Pinter, Moran, Haynes, Jay W., Mohyeldin, Ahmad M., C, Martin, Sargon, Alyssa B., Petrov, Anton S., Krishnamurthy, Ramanarayanan, Hud, Nicholas V., Williams, Loren Dean, Leman, Luke J.
Publicado no Nat Commun (2020)

Potential Agents for Treating Cystic Fibrosis: Cyclic Tetrapeptides That Restore Trafficking and Activity of ΔF508-CFTR

Por Hutt, Darren M., Olsen, Christian A., Vickers, Chris J., Herman, David, Chalfant, Monica A., Montero, Ana, Leman, Luke J., Burkle, Renner, Maryanoff, Bruce E., Balch, William E., Ghadiri, M. Reza
Publicado em 2011

Directed remodeling of the mouse gut microbiome inhibits the development of atherosclerosis

Por Chen, Poshen B., Black, Audrey S., Sobel, Adam L., Zhao, Yannan, Mukherjee, Purba, Molparia, Bhuvan, Moore, Nina E., Aleman Muench, German R., Wu, Jiejun, Chen, Weixuan, Pinto, Antonio F. M., Maryanoff, Bruce E., Saghatelian, Alan, Soroosh, Pejman, Torkamani, Ali, Leman, Luke J., Ghadiri, M. Reza
Publicado no Nat Biotechnol (2020)