In vivo efficacy of HDL-like nanolipid particles containing multivalent peptide mimetics of apolipoprotein A-I

We have observed that molecular constructs based on multiple apoA-I mimetic peptides attached to a branched scaffold display promising anti-atherosclerosis functions in vitro. Building on these promising results, we now describe chronic in vivo studies to assess anti-atherosclerotic efficacy of HDL-...

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Hlavní autoři: Zhao, Yannan, Black, Audrey S., Bonnet, David J., Maryanoff, Bruce E., Curtiss, Linda K., Leman, Luke J., Ghadiri, M. Reza
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2014
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4173998/
https://ncbi.nlm.nih.gov/pubmed/24975585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M049262
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