Self-Assembling Cyclic d,l-α-Peptides as Modulators of Plasma HDL Function. A Supramolecular Approach toward Antiatherosclerotic Agents

[Image: see text] There is great interest in developing new modes of therapy for atherosclerosis to treat coronary heart disease and stroke, particularly ones that involve modulation of high-density lipoproteins (HDLs). Here, we describe a new supramolecular chemotype for altering HDL morphology and...

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Publié dans:ACS Cent Sci
Auteurs principaux: Zhao, Yannan, Leman, Luke J., Search, Debra J., Garcia, Ricardo A., Gordon, David A., Maryanoff, Bruce E., Ghadiri, M. Reza
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2017
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5492419/
https://ncbi.nlm.nih.gov/pubmed/28691076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.7b00154
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