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Biomimetic Catalysis of Intermodular Aminoacyl Transfer

Intermodular aminoacyl transfer is the fundamental bond forming reaction in the biosynthesis of polypeptides by ribosomes and nonribosomal peptide synthetases (NRPS). Here we report the design and functional characterizations of short synthetic α-helical peptides that mimic the aminoacyl loading and...

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Main Authors: Wilcoxen, Keith M., Leman, Luke J., Weinberger, Dana A., Huang, Zheng-Zheng, Ghadiri, M. Reza
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453065/
https://ncbi.nlm.nih.gov/pubmed/17243796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja067124h
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