Flipping a Lipid-Linked Oligosaccharide? You Must Whip It!

Por Lehrman, Mark A.
Publicado no Trends Biochem Sci (2015)

Regulation of the dolichol pathway in human fibroblasts by the endoplasmic reticulum unfolded protein response

Por Doerrler, William T., Lehrman, Mark A.
Publicado em 1999

Analysis of Glycosylation in CDG-Ia Fibroblasts by Fluorophore-assisted Carbohydrate Electrophoresis: IMPLICATIONS FOR EXTRACELLULAR GLUCOSE AND INTRACELLULAR MANNOSE 6-PHOSPHATE

Por Gao, Ningguo, Shang, Jie, Lehrman, Mark A.
Publicado em 2005

Letter to the Glycoforum: Improved Protocols For Preparing Lipid-Linked And Related Saccharides For Fluorophore-Assisted Carbohydrate Electrophoresis (FACE)

Por Gao, Ningguo, Holmes, Justin, Lehrman, Mark A.
Publicado em 2013

Suppression of Rft1 Expression Does Not Impair the Transbilayer Movement of Man(5)GlcNAc(2)-P-P-Dolichol in Sealed Microsomes from Yeast

Por Rush, Jeffrey S., Gao, Ningguo, Lehrman, Mark A., Matveev, Sergey, Waechter, Charles J.
Publicado em 2009

Translation attenuation by PERK balances ER glycoprotein synthesis with lipid-linked oligosaccharide flux

Por Shang, Jie, Gao, Ningguo, Kaufman, Randal J., Ron, David, Harding, Heather P., Lehrman, Mark A.
Publicado em 2007

5-Thiomannosides block the biosynthesis of dolichol-linked oligosaccharides and mimic class I congenital disorders of glycosylation

Por Zandberg, Wesley F, Gao, Ningguo, Kumarasamy, Jayakanthan, Lehrman, Mark A, Seidah, Nabil G, Pinto, B Mario
Publicado em 2012

Mutation in LDL Receptor: Alu-Alu Recombination Deletes Exons Encoding Transmembrane and Cytoplasmic Domains

Por Lehrman, Mark A., Schneider, Wolfgang J., Südhof, Thomas C., Brown, Michael S., Goldstein, Joseph L., Russell, David W.
Publicado no Science (1985)

Nogo-B receptor is necessary for cellular dolichol biosynthesis and protein N-glycosylation

Por Harrison, Kenneth D, Park, Eon Joo, Gao, Ningguo, Kuo, Andrew, Rush, Jeffrey S, Waechter, Charles J, Lehrman, Mark A, Sessa, William C
Publicado em 2011

Increased sensitivity to glucose starvation correlates with downregulation of glycogen phosphorylase isoform PYGB in tumor cell lines resistant to 2-deoxy-d-glucose

Por Philips, Katherine B., Kurtoglu, Metin, Leung, Howard J., Liu, Huaping, Gao, Ningguo, Lehrman, Mark A., Murray, Timothy G., Lampidis, Theodore J.
Publicado no Cancer Chemother Pharmacol (2013)

Requirement of the Lec35 Gene for All Known Classes of Monosaccharide-P-Dolichol-dependent Glycosyltransferase Reactions in Mammals

Por Anand, Monika, Rush, Jeffrey S., Ray, Sutapa, Doucey, Marie-Agnes, Weik, Jennifer, Ware, Felecia E., Hofsteenge, Jan, Waechter, Charles J., Lehrman, Mark A.
Publicado em 2001

Mcl-1 downregulation leads to the heightened sensitivity exhibited by BCR-ABL positive ALL to induction of energy and ER-stress

Por Leclerc, Guy J., DeSalvo, Joanna, Du, Jianfeng, Gao, Ningguo, Leclerc, Gilles M., Lehrman, Mark A., Lampidis, Theodore J., Barredo, Julio C
Publicado no Leuk Res (2015)

A zebrafish model of congenital disorders of glycosylation with phosphomannose isomerase deficiency reveals an early opportunity for corrective mannose supplementation

Por Chu, Jaime, Mir, Alexander, Gao, Ningguo, Rosa, Sabrina, Monson, Christopher, Sharma, Vandana, Steet, Richard, Freeze, Hudson H., Lehrman, Mark A., Sadler, Kirsten C.
Publicado em 2013

Glycoprotein Biosynthesis in a Eukaryote Lacking the Membrane Protein Rft1

Por Jelk, Jennifer, Gao, Ningguo, Serricchio, Mauro, Signorell, Aita, Schmidt, Remo S., Bangs, James D., Acosta-Serrano, Alvaro, Lehrman, Mark A., Bütikofer, Peter, Menon, Anant K.
Publicado em 2013

Antiangiogenic Activity of 2-Deoxy-D-Glucose

Por Merchan, Jaime R., Kovács, Krisztina, Railsback, Jaclyn W., Kurtoglu, Metin, Jing, Yuqi, Piña, Yolanda, Gao, Ningguo, Murray, Timothy G., Lehrman, Mark A., Lampidis, Theodore J.
Publicado em 2010

A zebrafish model of PMM2-CDG reveals altered neurogenesis and a substrate-accumulation mechanism for N-linked glycosylation deficiency

Por Cline, Abigail, Gao, Ningguo, Flanagan-Steet, Heather, Sharma, Vandana, Rosa, Sabrina, Sonon, Roberto, Azadi, Parastoo, Sadler, Kirsten C., Freeze, Hudson H., Lehrman, Mark A., Steet, Richard
Publicado em 2012

Cytosolic nuclease TREX1 regulates oligosaccharyltransferase activity independent of nuclease activity to suppress immune activation

Por Hasan, Maroof, Fermaintt, Charles S., Gao, Ningguo, Sakai, Tomomi, Miyazaki, Takuya, Jiang, Sixin, Li, Quan-Zhen, Atkinson, John P., Morse, Herbert C., Lehrman, Mark A., Yan, Nan
Publicado no Immunity (2015)

Mannose-6-phosphate regulates destruction of lipid-linked oligosaccharides

Por Gao, Ningguo, Shang, Jie, Huynh, Dang, Manthati, Vijaya L., Arias, Carolina, Harding, Heather P., Kaufman, Randal J., Mohr, Ian, Ron, David, Falck, John R., Lehrman, Mark A.
Publicado em 2011

A mutation in the human MPDU1 gene causes congenital disorder of glycosylation type If (CDG-If)

Por Kranz, Christian, Denecke, Jonas, Lehrman, Mark A., Ray, Sutapa, Kienz, Petra, Kreissel, Gunilla, Sagi, Dijana, Peter-Katalinic, Jasna, Freeze, Hudson H., Schmid, Thomas, Jackowski-Dohrmann, Sabine, Harms, Erik, Marquardt, Thorsten
Publicado em 2001

The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism

Por Deng, Yingfeng, Wang, Zhao V., Tao, Caroline, Gao, Ningguo, Holland, William L., Ferdous, Anwarul, Repa, Joyce J., Liang, Guosheng, Ye, Jin, Lehrman, Mark A., Hill, Joseph A., Horton, Jay D., Scherer, Philipp E.
Publicado em 2012