The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism

Postprandially, the liver experiences an extensive metabolic reprogramming that is required for the switch from glucose production to glucose assimilation. Upon refeeding, the unfolded protein response (UPR) is rapidly, though only transiently, activated. Activation of the UPR results in a cessation...

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Hlavní autoři: Deng, Yingfeng, Wang, Zhao V., Tao, Caroline, Gao, Ningguo, Holland, William L., Ferdous, Anwarul, Repa, Joyce J., Liang, Guosheng, Ye, Jin, Lehrman, Mark A., Hill, Joseph A., Horton, Jay D., Scherer, Philipp E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533268/
https://ncbi.nlm.nih.gov/pubmed/23257357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62819
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