XBP1-LOX Axis is critical in ER stress-induced growth of lung adenocarcinoma in 3D culture

Rapid growth of tumor cells needs to consume large amounts of oxygen and glucose, due to lack of blood supply within the tumor, cells live in an environment that lack of oxygen and nutrients. This environment results in endoplasmic reticulum (ER) stress and activates the UPR (unfolded protein respon...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Yang, Yi, Cheng, Bai-Jun, Jian, Hong, Chen, Zhi-Wei, Zhao, Yi, Yu, Yong-Feng, Li, Zi-Ming, Liao, Mei-Lin, Lu, Shun
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340705/
https://ncbi.nlm.nih.gov/pubmed/28337298
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