XBP1-LOX Axis is critical in ER stress-induced growth of lung adenocarcinoma in 3D culture

Rapid growth of tumor cells needs to consume large amounts of oxygen and glucose, due to lack of blood supply within the tumor, cells live in an environment that lack of oxygen and nutrients. This environment results in endoplasmic reticulum (ER) stress and activates the UPR (unfolded protein respon...

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Dades bibliogràfiques
Publicat a:Am J Transl Res
Autors principals: Yang, Yi, Cheng, Bai-Jun, Jian, Hong, Chen, Zhi-Wei, Zhao, Yi, Yu, Yong-Feng, Li, Zi-Ming, Liao, Mei-Lin, Lu, Shun
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340705/
https://ncbi.nlm.nih.gov/pubmed/28337298
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