The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism

Postprandially, the liver experiences an extensive metabolic reprogramming that is required for the switch from glucose production to glucose assimilation. Upon refeeding, the unfolded protein response (UPR) is rapidly, though only transiently, activated. Activation of the UPR results in a cessation...

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Detalhes bibliográficos
Main Authors: Deng, Yingfeng, Wang, Zhao V., Tao, Caroline, Gao, Ningguo, Holland, William L., Ferdous, Anwarul, Repa, Joyce J., Liang, Guosheng, Ye, Jin, Lehrman, Mark A., Hill, Joseph A., Horton, Jay D., Scherer, Philipp E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533268/
https://ncbi.nlm.nih.gov/pubmed/23257357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62819
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