Peptide-based immunotherapy of experimental autoimmune encephalomyelitis without anaphylaxis

Por Leech, Melanie D, Chung, Chen-Yen, Culshaw, Abigail, Anderton, Stephen M
Publicado em 2007

Recognition of a High Affinity MHC Class I-Restricted Epitope of Myelin Oligodendrocyte Glycoprotein by CD8(+) T Cells Derived from Autoantigen-Deficient Mice

Por Leech, Melanie D., Carrillo-Vico, Antonio, Liblau, Roland S., Anderton, Stephen M.
Publicado em 2011

PD-1 signalling in CD4(+) T cells restrains their clonal expansion to an immunogenic stimulus, but is not critically required for peptide-induced tolerance

Por Konkel, Joanne E, Frommer, Friederike, Leech, Melanie D, Yagita, Hideo, Waisman, Ari, Anderton, Stephen M
Publicado em 2010

1,25-Dihydroxyvitamin D(3)-Conditioned CD11c+ Dendritic Cells are Effective Initiators of CNS Autoimmune Disease

Por Besusso, Dario, Saul, Louise, Leech, Melanie D., O’Connor, Richard A., MacDonald, Andrew S., Anderton, Stephen M., Mellanby, Richard J.
Publicado no Front Immunol (2015)

Cutting Edge: Th1 Cells Facilitate the Entry of Th17 Cells to the Central Nervous System during Experimental Autoimmune Encephalomyelitis

Por O’Connor, Richard A., Prendergast, Catriona T., Sabatos, Catherine A., Lau, Clement W. Z., Leech, Melanie D., Wraith, David C., Anderton, Stephen M.
Publicado em 2008

IL-6-dependent autoimmune disease: dendritic cells as a sufficient, but transient, source

Por Leech, Melanie D., Barr, Tom A., Turner, Darryl G., Brown, Sheila, O’Connor, Richard A., Gray, David, Mellanby, Richard J., Anderton, Stephen M.
Publicado em 2012

TLR-4 ligation of dendritic cells is sufficient to drive pathogenic T cell function in experimental autoimmune encephalomyelitis

Por Mellanby Richard J, Cambrook Helen, Turner Darryl G, O’Connor Richard A, Leech Melanie D, Kurschus Florian C, MacDonald Andrew S, Arnold Bernd, Anderton Stephen M
Publicado em 2012-10-01

TLR-4 ligation of dendritic cells is sufficient to drive pathogenic T cell function in experimental autoimmune encephalomyelitis

Por Mellanby, Richard J, Cambrook, Helen, Turner, Darryl G, O’Connor, Richard A, Leech, Melanie D, Kurschus, Florian C, MacDonald, Andrew S, Arnold, Bernd, Anderton, Stephen M
Publicado em 2012

Combination peptide immunotherapy based on T‐cell epitope mapping reduces allergen‐specific IgE and eosinophilia in allergic airway inflammation

Por Mackenzie, Karen J., Fitch, Paul M., Leech, Melanie D., Ilchmann, Anne, Wilson, Claire, McFarlane, Amanda J., Howie, Sarah E.M., Anderton, Stephen M., Schwarze, Jürgen
Publicado em 2013

Effector and central memory T helper 2 cells respond differently to peptide immunotherapy

Por Mackenzie, Karen J., Nowakowska, Dominika J., Leech, Melanie D., McFarlane, Amanda J., Wilson, Claire, Fitch, Paul M., O’Connor, Richard A., Howie, Sarah E. M., Schwarze, Jürgen, Anderton, Stephen M.
Publicado em 2014

Epigenetic modification of the PD-1 (Pdcd1) promoter in effector CD4(+) T cells tolerized by peptide immunotherapy

Por McPherson, Rhoanne C, Konkel, Joanne E, Prendergast, Catriona T, Thomson, John P, Ottaviano, Raffaele, Leech, Melanie D, Kay, Oliver, Zandee, Stephanie E J, Sweenie, Claire H, Wraith, David C, Meehan, Richard R, Drake, Amanda J, Anderton, Stephen M
Publicado no eLife (2014)

IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases

Por Shen, Ping, Roch, Toralf, Lampropoulou, Vicky, O’Connor, Richard A., Stervbo, Ulrik, Hilgenberg, Ellen, Ries, Stefanie, Dang, Van Duc, Jaimes, Yarúa, Daridon, Capucine, Li, Rui, Jouneau, Luc, Boudinot, Pierre, Wilantri, Siska, Sakwa, Imme, Miyazaki, Yusei, Leech, Melanie D., McPherson, Rhoanne C., Wirtz, Stefan, Neurath, Markus, Hoehlig, Kai, Meinl, Edgar, Grützkau, Andreas, Grün, Joachim R., Horn, Katharina, Kühl, Anja A., Dörner, Thomas, Bar-Or, Amit, Kaufmann, Stefan H.E., Anderton, Stephen M., Fillatreau, Simon
Publicado no Nature (2014)