1,25-Dihydroxyvitamin D(3)-Conditioned CD11c+ Dendritic Cells are Effective Initiators of CNS Autoimmune Disease

Dendritic cells (DC) play a crucial role in regulating T cell activation. Due to their capacity to shape the immune response, tolerogenic DC have been used to treat autoimmune diseases. In this study, we examined whether 1,25 dihydroxyvitamin D(3)-conditioned bone marrow-derived DC (VitD-BMDC) were...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Besusso, Dario, Saul, Louise, Leech, Melanie D., O’Connor, Richard A., MacDonald, Andrew S., Anderton, Stephen M., Mellanby, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650204/
https://ncbi.nlm.nih.gov/pubmed/26635791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00575
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