IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases

B lymphocytes have critical roles as positive and negative regulators of immunity. Their inhibitory function has so far been associated primarily with interleukin (IL)-10 because B cell-derived IL-10 can protect against autoimmune disease and increase susceptibility to pathogens(1,2). Here, we ident...

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Udgivet i:Nature
Main Authors: Shen, Ping, Roch, Toralf, Lampropoulou, Vicky, O’Connor, Richard A., Stervbo, Ulrik, Hilgenberg, Ellen, Ries, Stefanie, Dang, Van Duc, Jaimes, Yarúa, Daridon, Capucine, Li, Rui, Jouneau, Luc, Boudinot, Pierre, Wilantri, Siska, Sakwa, Imme, Miyazaki, Yusei, Leech, Melanie D., McPherson, Rhoanne C., Wirtz, Stefan, Neurath, Markus, Hoehlig, Kai, Meinl, Edgar, Grützkau, Andreas, Grün, Joachim R., Horn, Katharina, Kühl, Anja A., Dörner, Thomas, Bar-Or, Amit, Kaufmann, Stefan H.E., Anderton, Stephen M., Fillatreau, Simon
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260166/
https://ncbi.nlm.nih.gov/pubmed/24572363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12979
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