IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases

B lymphocytes have critical roles as positive and negative regulators of immunity. Their inhibitory function has so far been associated primarily with interleukin (IL)-10 because B cell-derived IL-10 can protect against autoimmune disease and increase susceptibility to pathogens(1,2). Here, we ident...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Shen, Ping, Roch, Toralf, Lampropoulou, Vicky, O’Connor, Richard A., Stervbo, Ulrik, Hilgenberg, Ellen, Ries, Stefanie, Dang, Van Duc, Jaimes, Yarúa, Daridon, Capucine, Li, Rui, Jouneau, Luc, Boudinot, Pierre, Wilantri, Siska, Sakwa, Imme, Miyazaki, Yusei, Leech, Melanie D., McPherson, Rhoanne C., Wirtz, Stefan, Neurath, Markus, Hoehlig, Kai, Meinl, Edgar, Grützkau, Andreas, Grün, Joachim R., Horn, Katharina, Kühl, Anja A., Dörner, Thomas, Bar-Or, Amit, Kaufmann, Stefan H.E., Anderton, Stephen M., Fillatreau, Simon
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260166/
https://ncbi.nlm.nih.gov/pubmed/24572363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12979
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