LAG-3 Inhibitory Receptor Expression Identifies Immunosuppressive Natural Regulatory Plasma Cells

B lymphocytes can suppress immunity through interleukin (IL)-10 production in infectious, autoimmune, and malignant diseases. Here, we have identified a natural plasma cell subset that distinctively expresses the inhibitory receptor LAG-3 and mediates this function in vivo. These plasma cells also e...

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I publikationen:Immunity
Huvudupphovsmän: Lino, Andreia C., Dang, Van Duc, Lampropoulou, Vicky, Welle, Anna, Joedicke, Jara, Pohar, Jelka, Simon, Quentin, Thalmensi, Jessie, Baures, Aurelia, Flühler, Vinciane, Sakwa, Imme, Stervbo, Ulrik, Ries, Stefanie, Jouneau, Luc, Boudinot, Pierre, Tsubata, Takeshi, Adachi, Takahiro, Hutloff, Andreas, Dörner, Thomas, Zimber-Strobl, Ursula, de Vos, Alex F., Dahlke, Katja, Loh, Gunnar, Korniotis, Sarantis, Goosmann, Christian, Weill, Jean-Claude, Reynaud, Claude-Agnès, Kaufmann, Stefan H.E., Walter, Jörn, Fillatreau, Simon
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cell Press 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057275/
https://ncbi.nlm.nih.gov/pubmed/30005826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.06.007
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