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Treatment of ongoing autoimmune encephalomyelitis with activated B-cell progenitors maturing into regulatory B cells

The influence of signals perceived by immature B cells during their development in bone marrow on their subsequent functions as mature cells are poorly defined. Here, we show that bone marrow cells transiently stimulated in vivo or in vitro through the Toll-like receptor 9 generate proB cells (CpG-p...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Korniotis, Sarantis, Gras, Christophe, Letscher, Hélène, Montandon, Ruddy, Mégret, Jérôme, Siegert, Stefanie, Ezine, Sophie, Fallon, Padraic G., Luther, Sanjiv A., Fillatreau, Simon, Zavala, Flora
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942579/
https://ncbi.nlm.nih.gov/pubmed/27396388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12134
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