Toll-like receptor-9 stimulated plasmacytoid dendritic cell precursors suppress autoimmune neuroinflammation in a murine model of multiple sclerosis

Early innate education of hematopoietic progenitors within the bone marrow (BM) stably primes them for either trained immunity or instead immunoregulatory functions. We herein demonstrate that in vivo or in vitro activation within the BM via Toll-like receptor-9 generates a population of plasmacytoi...

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Publicat a:Sci Rep
Autors principals: Letscher, Hélène, Agbogan, Viviane A., Korniotis, Sarantis, Gastineau, Pauline, Tejerina, Emmanuel, Gras, Christophe, Mégret, Jérôme, Moe, Alison, Drobyski, William R., Zavala, Flora
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910458/
https://ncbi.nlm.nih.gov/pubmed/33637789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84023-0
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