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Positive and negative regulation of T cell responses by fibroblastic reticular cells within paracortical regions of lymph nodes

Fibroblastic reticular cells (FRC) form the structural backbone of the T cell rich zones in secondary lymphoid organs (SLO), but also actively influence the adaptive immune response. They provide a guidance path for immigrating T lymphocytes and dendritic cells (DC) and are the main local source of...

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Detalhes bibliográficos
Main Authors: Siegert, Stefanie, Luther, Sanjiv A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438460/
https://ncbi.nlm.nih.gov/pubmed/22973278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00285
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