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Cutting Edge: Th1 Cells Facilitate the Entry of Th17 Cells to the Central Nervous System during Experimental Autoimmune Encephalomyelitis

It has recently been proposed that experimental autoimmune encephalomyelitis, once considered the classical Th1 disease, is predominantly Th17 driven. In this study we show that myelin-reactive Th1 preparations devoid of contaminating IL-17(+) cells are highly pathogenic. In contrast, Th17 preparati...

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Detalhes bibliográficos
Main Authors: O’Connor, Richard A., Prendergast, Catriona T., Sabatos, Catherine A., Lau, Clement W. Z., Leech, Melanie D., Wraith, David C., Anderton, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2619513/
https://ncbi.nlm.nih.gov/pubmed/18768826
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