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Cutting Edge: Ikaros Is a Regulator of Th2 Cell Differentiation

Ikaros, a hematopoietic transcription factor, has well defined effects on early lymphocyte development in the bone marrow and thymus. In this study we demonstrate that Ikaros is a positive regulator of Th2 cytokine gene expression in peripheral T cells. CD4(+) T cells from naive Ikaros(null) mice cu...

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主要な著者: Quirion, Mary R., Gregory, Gregory D., Umetsu, Sarah E., Winandy, Susan, Brown, Melissa A.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718557/
https://ncbi.nlm.nih.gov/pubmed/19124715
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