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Mast cell IL-4 expression is regulated by Ikaros and influences encephalitogenic Th1 responses in EAE

When exposed to a pathogen, a naive CD4(+) T cell is forced to make a cell fate decision that leads to a polarized population of Th1 IFN-γ– or Th2 IL-4– producing cells. Although IL-4 has traditionally been considered a factor that promotes Th2 cell differentiation, recent evidence has demonstrated...

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Bibliografski detalji
Glavni autori: Gregory, Gregory D., Raju, Shveta S., Winandy, Susan, Brown, Melissa A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440706/
https://ncbi.nlm.nih.gov/pubmed/16628252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27227
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