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Mast cell IL-4 expression is regulated by Ikaros and influences encephalitogenic Th1 responses in EAE
When exposed to a pathogen, a naive CD4(+) T cell is forced to make a cell fate decision that leads to a polarized population of Th1 IFN-γ– or Th2 IL-4– producing cells. Although IL-4 has traditionally been considered a factor that promotes Th2 cell differentiation, recent evidence has demonstrated...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1440706/ https://ncbi.nlm.nih.gov/pubmed/16628252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27227 |
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